When The Body Attacks Itself
The immune system is what keeps most people's bodies healthy and free of disease, but for as many as 23 million Americans, it is a cause of disease, too. In autoimmune disorders, the system goes haywire, mistaking the body's own tissues for foreign invaders and destroying them.
A New Era Begins
Stem-cell research is divided into two major camps: one focused on cells from adults, the other on the controversial technique that destroys embryos. But important research published Sunday supports the idea of a third way, a new category of stem cells that are readily available, perhaps ethically trouble-free and possibly as powerful and flexible in function as their embryonic counterparts: "amniotic-fluid stem cells," found in both the placenta and the liquid that surrounds growing...
Stem Cells Are Where It's At
Seventeen years ago, Richard Burt, an immunologist at Northwestern University, had a crazy idea. What if he could press the "restart" button on his patients, destroying their faulty immune systems and building them new ones?
A Terrible Mystery
Thomas Insel spent years training as a psychiatrist in the 1970s, and in all that time he saw not one child with autism. In 1985, curiosity sent him searching; it took several phone calls to find a single patient.
Drugs: Family Docs Join the Drug War
In the war on drugs, the White House has tried just about every weapon--punitive policy, rehab programs, ads featuring fried eggs. For its next strike, it has some new recruits: family doctors.
The Writer Will See You Now
It's not an official medical report, and it won't help doctors treat the patient it's about, but Dr. Dena Rifkin's write-up tells a story that the dry clinical language of medicine never could. "There are startling moments that you don't forget," it begins, and clearly this was one of them—a night in which a young Rifkin, not even yet an M.D., stumbled out of sleep and into a patient's room to find him soaked in blood. "The patient looked up at me, and opened his mouth as if to speak," she...
A Piece of the Puzzle
Earlier this week, scientists announced that they had for the first time pinpointed a common version of a gene that strongly increases the risk for autism.
Case Study: A Standard Approach
It's been 124 years since caleb Cooley Dickinson, cousin of the poet Emily, endowed the hospital in Northampton, Mass., that bears his name--and he'd barely recognize the modern institution it has become.
They Call Her 'Lucy's Daughter'
It's been 3.2 million years since she died--and 32 since she was unearthed from the Ethiopian desert and christened after a Beatles song--but the prehuman fossil known as Lucy can still draw a crowd.
Med-School Makeover
Dr. A. Scott Pearson's patient had a problem--two problems, actually, and only one of them seemed fixable by a surgeon. The patient, an elderly man, needed to have a tumor removed from his colon.
HIV: Learning From Monkeys and Chimps
HIV, like any other virus, has one goal--and it isn't killing. The goal is to reproduce, and since viruses do that by hijacking their hosts' cells, they can't further their own existence after they've killed off those cells.
Science: Who's That Stunner?
Enlightened types say they're "self-aware" when they mean they're one with the universe. But for scientists who study animal behavior, the term "self-awareness" has always meant something much more down to earth.
Dolphins: 'Bob's in a Picture!'
According to scientific naming, the dolphin above is called Tursiops truncates, but it probably thinks it's named something more like "Bob." Marine biologists announced last week that dolphins compose their own unique signature whistles and clicks that identify them within their communities--or, put more simply, dolphins have names.Despite a wide range of pseudo-cultural and learning behaviors recently discovered across the animal kingdom, dolphins are one of only two animal species known to...
'Vintage' Bugs Return
Growing up in Peoria, Ill., in the 1950s, Lance Rodewald caught "measles and mumps and probably German measles," and though he doesn't remember suffering through any of them, his wife, Patricia, assures him they were all "absolutely miserable" experiences.
Videogames: Playing It Smart
Parents who worry about violent video-games would have loved last week's rankings on Amazon. Holding steady at No. 2 was Brain Age, a Nintendo DS game that features no shooting and lots of studying.
Physics: From Time To Time
Ronald Mallett, a University of Connecticut physics professor, thinks time travel is possible--and he's designed an experiment that could do it. Basically, he wants to "swirl" empty space the way you'd swirl coffee in a cup, using a laser as the stirrer.
Leading the Hunt For Cancer Genes
Thirty years ago, Joan Brugge was a bright college student on her way to a career in math. But when her sister developed a fatal brain tumor, she turned to the library and was stunned to find that there was "basically nothing known" about the cause of the illness.
Spring Fevers
A few weeks ago Ashley Ramirez was visiting a couple of close friends in Omaha, Neb., who were hospitalized following a car accident when she started running a fever and noticed a small lump on her neck.
Taking to the Air
Whatever you call the new Transition, says its inventor, Carl Dietrich, just don't call it a flying car--even if it's the closest thing to one that exists.
Inventions: Taking to The Air
Look, in the sky--it's a bird! It's a plane! It's... a personal air vehicle? Whatever you call the new Transition, says its inventor, Carl Dietrich, just don't call it a flying car--even if it's the closest thing to one that exists.
Gut Flora? Great!
You may use antibacterial dish soap and wash your hands every time you sneeze, but Jeffrey Gordon wants you to know that you're crawling with germs. Gordon, the director of the Center for Genome Sciences at Washington University in St.
The Gene Hunter
To call Dr. Tom Hudson modest would be putting it, well, modestly. One of the world's premier investigators of genetically linked disease, he discovered four years ago that DNA is inherited in chunks--the principle at the heart of the HapMap, the recently completed project describing millions of variations in the human genome.
Immunity's Master Controller
Like many pharmaceutical researchers, Dr. Arthur Krieg is working on a cure for cancer. He also hopes to eradicate AIDS, lupus, hepatitis C, even allergies.
Eggs, Lies, Stem Cells
Hwang Woo-Suk may be a scientist, but in South Korea, he's virtually a rock-and-roll star. The first researcher to extract stem cells from a cloned human embryo, Hwang has an Internet fan club (its women are especially enthusiastic) and a worldwide reputation.
Analyze These!
Considering how few people use higher math in their lives, or even remember much of it from high school, the popularity of books on chaos theory and number theory and higher-dimensional geometry is, well, a paradox.
Medicine: The Future Arrives Early
In science, revolutions almost always take longer than their instigators expect--we're still waiting for our flying cars--so when National Institutes of Health director Dr.
Algae: So Has It Called Yet?
Birds do it. Bees do it. But placozoans? Since they were discovered in a saltwater aquarium 100 years ago, these simplest of animals have been thought of as, well, just not that into each other.
REBUILDING THE HEART
A million lonely ballads notwithstanding, with time, the human heart can recover from an emotional wound. In medicine, however, the prognosis is often bleaker, and time only makes a physical injury worse.
STUDY: EYE ON THE STORM
Since the days of Homer, sailors have theorized about the signals of a coming storm (the presence of dogs, cormorants or whistling sailors) and the signals of calm waters (black cats, swallows or, oddly enough, naked women).
SHUTTLE UPS AND DOWNS
It is NASA's old reliable, the craft the agency depends on when it needs to prove something big. Discovery was the shuttle that delivered the Hubble telescope and 77-year-old John Glenn into space, and revived NASA as the first ship to launch (in 1988) after the Challenger explosion two years earlier.